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Medical use of hydroxypropyl β-cyclodextrin

Jun. 09, 2020

Due to the low surface activity, low hemolytic activity and non-irritation to muscles, Hydroxypropyl β-cyclodextrin is considered an ideal pharmaceutical excipient and solubilizer in injections in pharmaceutical industry. It works to solubilize water-insoluble drugs, enhance drug stability, improve drug bio-availability (improve efficacy or lower dosage of drugs), moderate and control drug release, and can also help to diminish the toxicity and side effects of drugs. Further, Hydroxypropyl β-cyclodextrin can be applied as a drug carrier in oral medications, injections, mucosal drug delivery system, transdermal drug delivery system, and targeted lipophilic drugs. Also, it is suitable as a protectant and stabilizer for proteins.

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