Sulfobutyl Ether Beta Cyclodextrin Sodium Salt

Sulfobutyl Ether Beta Cyclodextrin Sodium Salt (CAS 182410-00-0) is a highly water-soluble anionic derivative of beta-cyclodextrin. This pharmaceutical-grade excipient acts as a solubilizer, complexing agent, and stabilizer for poorly soluble drugs, enhancing bioavailability, safety, and stability.

Sulfobutyl Ether Beta Cyclodextrin Sodium Salt is produced by alkylating beta-cyclodextrin with 1,4-butanesultone under alkaline conditions. The resulting anionic derivative forms inclusion complexes with drug molecules, reducing renal toxicity, minimizing hemolysis, controlling release rates, and masking unpleasant tastes or odors. It is widely used in injectable, oral, nasal, and ophthalmic formulations.

Company Introduction

Xi'an Deli Biochemical Industry Co., Ltd. is a high-tech manufacturer specializing in cyclodextrin derivatives, including Hydroxypropyl Beta Cyclodextrin (HPBCD) and Sulfobutyl Ether Beta Cyclodextrin Sodium Salt (SBECD). Established in 1999, the company operates dedicated production lines with an annual capacity of over 200 tons for SBECD and 500 tons for HPBCD. Quality management follows ISO 9001:2015 standards, ensuring pharmaceutical-grade compliance and global supply reliability.

Specifications

[CAS No]: 182410-00-0
[Molecular Formula]: C42H70-nO35•(C4H8SO3Na)n
[Grade]: Injection Grade
[Appearance]: White to off-white amorphous powder
[Solubility]: Freely soluble in water; sparingly soluble in methanol; practically insoluble in ethanol and other organic solvents
[Storage]: Sealed preservation, cool and dry place
[Period of Validity]: 36 months
[Applications]: Injectable, oral, nasal, ophthalmic, and parenteral drug formulations
[Packaging]: 500 g/bag; 1 kg/bag; 10 kg/drum or customized

COA / Quality Assurance

Each batch of Sulfobutyl Ether Beta Cyclodextrin Sodium Salt undergoes rigorous testing, including assay, endotoxin levels, microbial limits, degree of substitution, residual solvents, and impurity profiles to ensure USP and EP compliance.

Product Applications

Sulfobutyl Ether Beta Cyclodextrin Sodium Salt is commonly used in antifungal, antiviral, cardiovascular, and oncology drug formulations. It enhances solubility of poorly soluble drugs, reduces renal toxicity, minimizes hemolysis, and improves patient compliance. The excipient is compatible with intravenous, intramuscular, nasal, oral, and ophthalmic delivery systems.

FAQ

Q: Is Xi'an Deli Biochemical the manufacturer of Sulfobutyl Ether Beta Cyclodextrin Sodium Salt?
A: Yes, Xi'an Deli Biochemical Industry Co., Ltd. is the manufacturer of Sulfobutyl Ether Beta Cyclodextrin Sodium Salt and other cyclodextrin derivatives.

Q: Are samples available?
A: Yes, free samples are available for evaluation upon request.

Q: What is the batch and annual production capacity?
A: Batch production is 2.5 tons, with annual capacity over 200 tons.

Q: What documentation is provided?
A: COA, MSDS, stability data, and technical dossiers are available for all Sulfobutyl Ether Beta Cyclodextrin Sodium Salt batches.

Q: Shipping options?
A: Global shipping is available by express, air, or sea.