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Hydroxypropyl Betadex INJECTION GRADE
[Product Name]: Hydroxypropyl Βetadex CAS 128446-35-5
[CAS NO]: 128446-35-5
[DMF]: DMF 034772[Period of validity]: 36 months
Hydroxypropyl Betadex INJECTION GRADE is widely used in pharmaceutical applications due to its ability to enhance the solubility and stability of various drugs. Here are some key applications:
1. SolubilizingHPBCD is used to increase the solubility of poorly water-soluble drugs, making them more bioavailable. This is particularly useful for intravenous and intramuscular injections where high solubility is crucial.
2. Stabilizing: HPBCD helps stabilize drugs that are prone to degradation. It forms inclusion complexes with drug molecules, protecting them from environmental factors such as light, heat, and oxidation.
3. Reducing: HPBCD can reduce the irritation caused by some injectable drugs. By forming inclusion complexes, it can encapsulate irritating molecules, minimizing their contact with tissues.
4. Controlled: HPBCD can be used in formulations to control the release rate of the active pharmaceutical ingredient, providing a more consistent therapeutic effect.
5. Compatibility with Biological Systems: Hydroxypropyl Betadex INJECTION GRADE is biocompatible and less toxic, making it suitable for use in injectable formulations.
6. Applications in Specific Drugs: HPBCD is used in the formulation of various injectable drugs, such as itraconazole, docetaxel, and other lipophilic drugs that require enhanced solubility and stability for effective therapeutic action.
These applications make Hydroxypropyl Betadex INJECTION GRADE a versatile and valuable excipient in the pharmaceutical industry, improving the efficacy and safety of injectable medications.
